利用Mn(III)salen催化剂催化下氧化(Z)烯烃不对称合成环氧化物的反应。

反应机理

首先氧化Mn(III)-salen络合物得到Mn(v)活性中间体，反应的对映选择性可以由Jacobsen提出的烯烃从催化剂的顶端进行反应 或Katsuki提出的从侧上方进行反应来解释。

有三种可能的反应机理：

反应实例

参考文献

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编译自：Name Reactions （A Collection of Detailed Reaction Mechanisms）, Jie Jack Li, Jacobsen–Katsuki epoxidation，page 329-330.